Dataset on transcriptomic profiling of cholestatic liver injury induced by food additives and a cosmetic ingredient.
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ABSTRACT:
SUBMITTER: Gijbels E
PROVIDER: S-EPMC8461341 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
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Dataset on transcriptomic profiling of cholestatic liver injury induced by food additives and a cosmetic ingredient.
Gijbels Eva E Devisscher Lindsey L Vinken Mathieu M
Data in brief 20210917
The provided dataset describes the differential gene expression profile of human hepatoma HepaRG cells cultured in monolayer configuration upon treatment with chemical compounds with cholestatic potential, including food additives sunset yellow and tartrazine and cosmetic ingredient triclosan, while being exposed to a highly concentrated bile acid mixture. Whole genome microarray Affymetrix Human U133 plus 2.0 was used to obtain the raw data followed by normalization, summarization and backgroun ...[more]
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