Recruitment order of motor neurons promoted by epidural stimulation in individuals with spinal cord injury.

ABSTRACT: Spinal cord epidural stimulation (scES) combined with activity-based training can promote motor function recovery in individuals with motor complete spinal cord injury (SCI). The characteristics of motor neuron recruitment, which influence different aspects of motor control, are still unknown when motor function is promoted by scES. Here, we enrolled five individuals with chronic motor complete SCI implanted with an scES unit to study the recruitment order of motor neurons during standing enabled by scES. We recorded high-density electromyography (HD-EMG) signals on the vastus lateralis muscle and inferred the order of recruitment of motor neurons from the relation between amplitude and conduction velocity of the scES-evoked EMG responses along the muscle fibers. Conduction velocity of scE

SUBMITTER: Ibanez J 

PROVIDER: S-EPMC8461808 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature