Automation assisted anaerobic phenotyping for metabolic engineering.

ABSTRACT:

Background

Microorganisms can be metabolically engineered to produce a wide range of commercially important chemicals. Advancements in computational strategies for strain design and synthetic biological techniques to construct the designed strains have facilitated the generation of large libraries of potential candidates for chemical production. Consequently, there is a need for high-throughput laboratory scale techniques to characterize and screen these candidates to select strains for further investigation in large scale fermentation processes. Several small-scale fermentation techniques, in conjunction with laboratory automation have enhanced the throughput of enzyme and strain phenotyping experiments. However, such high throughput experimentation typically entails large operati

SUBMITTER: Raj K 

PROVIDER: S-EPMC8461876 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature