Implications derived from S-protein variants of SARS-CoV-2 from six continents.

ABSTRACT: The spike (S) protein is a critical determinant of the infectivity and antigenicity of SARS-CoV-2. Several mutations in the S protein of SARS-CoV-2 have already been detected, and their effect in immune system evasion and enhanced transmission as a cause of increased morbidity and mortality are being investigated. From pathogenic and epidemiological perspectives, S proteins are of prime interest to researchers. This study focused on the unique variants of S proteins from six continents: Asia, Africa, Europe, Oceania, South America, and North America. In comparison to the other five continents, Africa had the highest percentage of unique S proteins (29.1%). The phylogenetic relationship implies that unique S proteins from North America are significantly different from those of the other fiv

SUBMITTER: Hassan SS 

PROVIDER: S-EPMC8462006 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature