Urinary Exosomes Diagnosis of Urological Tumors: A Systematic Review and Meta-Analysis.

ABSTRACT:

Purpose

Exosomes could be released directly into the urine by the urological tumoral cells, so testing urinary exosomes has great potential for non-invasive diagnosis and monitor of urological tumors. The objective of this study is to systematically review and meta-analysis of urinary exosome for urological tumors diagnosis.

Materials and methods

A systematic review of the recent English-language literature was conducted according to the PRISMA statement recommendations (CRD42021250613) using PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases up to April 30, 2021. Risk-of-bias assessment was performed according to the QUADAS 2 tool. The true diagnostic value of urinary exosomes by calculating the number of true positive, false positive, true negative, and

SUBMITTER: Xu Y 

PROVIDER: S-EPMC8462303 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature