Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters.
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ABSTRACT:
SUBMITTER: Williamson BN
PROVIDER: S-EPMC8462347 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Publications
Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters.
Williamson Brandi N BN Prescott Joseph J Garrido Jose L JL Alvarez Raymond A RA Feldmann Heinz H Barría Maria I MI
Emerging infectious diseases 20211001 10
Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined treatment with 2 monoclonal antibodies protected Syrian hamsters when administered at midstage or late-stage disease. ...[more]
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