Systemic Conditions Associated with Severity of Dry Eye Signs and Symptoms in the Dry Eye Assessment and Management Study.

ABSTRACT:

Purpose

Certain systemic conditions are reported to be risk factors for dry eye disease (DED), but their associations with DED severity are not well studied. We evaluated whether systemic conditions reported to be DED risk factors are associated with severity of DED signs and symptoms.

Design

Secondary analysis of data from the Dry Eye Assessment and Management Study, a large-scale multicenter randomized clinical trial of patients with moderate to severe DED.

Participants

Five hundred thirty-five adult patients with moderate to severe DED from 27 United States centers.

Methods

Patients reported their medical history at baseline. They underwent ocular surface examinations and symptom evaluation using standardized protocols at baseline, 6 months, and 12 months. W

SUBMITTER: Yu K 

PROVIDER: S-EPMC8463420 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature