Transcatheter Compared With Surgical Aortic Valve Replacement in Patients With Previous Chest-Directed Radiation Therapy.

ABSTRACT:

Background

Cardiac surgery for radiation-induced valvular disease is associated with adverse outcomes. Transcatheter aortic valve replacement (TAVR) is increasingly used in patients with a history of chest-directed radiation therapy and aortic stenosis (CRT-AS).

Objectives

We examined outcomes of TAVR compared with surgical aortic valve replacement (SAVR) for patients with CRT-AS.

Methods

We identified 69 patients with CRT-AS who underwent TAVR from January 2012 to September 2018. Operative mortality, postoperative morbidities, and length of hospitalization were compared with 117 contemporaneous patients with CRT-AS who underwent isolated SAVR. Age-adjusted survival was evaluated by means of Cox proportional hazards modeling.

Results

Compared with SAVR patients

SUBMITTER: Yazdchi F 

PROVIDER: S-EPMC8463724 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature