Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study.

ABSTRACT:

Background

Radiation therapy (RT) for breast cancer increases risk of coronary artery disease (CAD). Women treated for left- vs right-sided breast cancer receive greater heart radiation exposure, which may further increase this risk. The risk of radiation-associated CAD specifically among younger breast cancer survivors is not well defined.

Objectives

The purpose of this study was to report CAD risk among participants in the Women's Environmental Cancer and Radiation Epidemiology Study.

Methods

A total of 1,583 women who were <55 years of age when diagnosed with breast cancer between 1985 and 2008 completed a cardiovascular health questionnaire. Risk of radiation-associated CAD was evaluated by comparing women treated with left-sided RT with women treated with right-s

SUBMITTER: Carlson LE 

PROVIDER: S-EPMC8463731 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature