Laminar dynamics of high amplitude beta bursts in human motor cortex.

ABSTRACT: Motor cortical activity in the beta frequency range is one of the strongest and most studied movement-related neural signals. At the single trial level, beta band activity is often characterized by transient, high amplitude, bursting events rather than slowly modulating oscillations. The timing of these bursting events is tightly linked to behavior, suggesting a more dynamic functional role for beta activity than previously believed. However, the neural mechanisms underlying beta bursts in sensorimotor circuits are poorly understood. To address this, we here leverage and extend recent developments in high precision MEG for temporally resolved laminar analysis of burst activity, combined with a neocortical circuit model that simulates the biophysical generators of the electrical currents wh

SUBMITTER: Bonaiuto JJ 

PROVIDER: S-EPMC8463839 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature