Restoring fertility in yeast hybrids: Breeding and quantitative genetics of beneficial traits.

ABSTRACT: Hybrids between species can harbor a combination of beneficial traits from each parent and may exhibit hybrid vigor, more readily adapting to new harsher environments. Interspecies hybrids are also sterile and therefore an evolutionary dead end unless fertility is restored, usually via auto-polyploidisation events. In the Saccharomyces genus, hybrids are readily found in nature and in industrial settings, where they have adapted to severe fermentative conditions. Due to their hybrid sterility, the development of new commercial yeast strains has so far been primarily conducted via selection methods rather than via further breeding. In this study, we overcame infertility by creating tetraploid intermediates of Saccharomyces interspecies hybrids to allow continuous multigenerational breeding.

SUBMITTER: Naseeb S 

PROVIDER: S-EPMC8463882 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature