Ventral striatal resting-state functional connectivity in adolescents is associated with earlier onset of binge drinking.

ABSTRACT:

Background

Earlier engagement in heavy drinking during adolescence is a risk factor for the development of alcohol use disorders later in life. Longitudinal studies in adolescents have linked brain structure and task-evoked function to future alcohol use; however, less is known about how intrinsic network-level interactions relate to future substance use during this developmental period.

Methods

In this prospective longitudinal study, resting-state functional connectivity of the ventral striatum, risky decision making, and sensation seeking were measured in 73 adolescents at baseline. Participants were between the ages of 14 and 15 and had no substantial history of substance use upon study entry. Follow-up interviews were conducted approximately every 3 months to assess the

SUBMITTER: Morales AM 

PROVIDER: S-EPMC8464521 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature