Neural basis of the visual working memory deficit in schizophrenia: Merging evidence from fMRI and EEG.

ABSTRACT: Although people with schizophrenia (PSZ) exhibit robust and reliable deficits in working memory (WM) capacity, the neural processes that give rise to this impairment remain poorly understood. One reason for this lack of clarity is that most studies employ a single neural recording modality-each with strengths and weaknesses-with few examples of integrating results across modalities. To address this gap, we conducted a secondary analysis that combined data from an overlapping set of subjects in previously published electroencephalographic and functional magnetic resonance imaging studies that used nearly identical working memory tasks (visual change detection). The prior studies found similar patterns of results for both posterior parietal BOLD activation and suppression of the alpha freque

SUBMITTER: Erickson MA 

PROVIDER: S-EPMC8464530 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature