Review and Meta-Analysis of the Evidence for Choosing between Specific Pyrethroids for Programmatic Purposes.

ABSTRACT: Pyrethroid resistance is widespread in malaria vectors. However, differential mortality in discriminating dose assays to different pyrethroids is often observed in wild populations. When this occurs, it is unclear if this differential mortality should be interpreted as an indication of differential levels of susceptibility within the pyrethroid class, and if so, if countries should consider selecting one specific pyrethroid for programmatic use over another. A review of evidence from molecular studies, resistance testing with laboratory colonies and wild populations, and mosquito behavioural assays were conducted to answer these questions. Evidence suggested that in areas where pyrethroid resistance exists, different results in insecticide susceptibility assays with specific pyrethroids cu

SUBMITTER: Lissenden N 

PROVIDER: S-EPMC8465213 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature