Consistency of spatial dynamics of HIV-1 and HCV among HIV-1/HCV coinfected drug users in China.

ABSTRACT:

Background

As the transmission routes of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) are similar, previous studies based on separate research on HIV-1 and HCV assumed a similar transmission pattern. However, few studies have focused on the possible correlation of the spatial dynamics of HIV-1 and HCV among HIV-1/HCV coinfected patients.

Methods

A total of 310 HIV-1/HCV coinfected drug users were recruited in Yingjiang and Kaiyuan prefectures, Yunnan Province, China. HIV-1 env, p17, pol and HCV C/E2, NS5B fragments were amplified and sequenced from serum samples. The genetic characteristics and spatial dynamics of HIV-1 and HCV were explored by phylogenetic, bootscanning, and phylogeographic analyses.

Results

Among HIV-1/HCV coinfected drug

SUBMITTER: Wang Y 

PROVIDER: S-EPMC8465760 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature