The Role of Polymorphisms in Collagen-Encoding Genes in Intervertebral Disc Degeneration.

ABSTRACT: (1) Background: The purpose of this review is to analyze domestic and foreign studies on the role of collagen-encoding genes polymorphism in the development of intervertebral discs (IVDs) degeneration in humans. (2) Methods: We have carried out a search for full-text articles published in e-Library, PubMed, Oxford Press, Clinical Case, Springer, Elsevier and Google Scholar databases. The search was carried out using keywords and their combinations. The search depth was 5 years (2016-2021). In addition, this review includes articles of historical interest. Despite an extensive search, it is possible that we might have missed some studies published in recent years. (3) Results: According to the data of genome-wide and associative genetic studies, the following candidate genes that play a rol

SUBMITTER: Trefilova VV 

PROVIDER: S-EPMC8465916 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature