Focality-Oriented Selection of Current Dose for Transcranial Direct Current Stimulation.

ABSTRACT: Background: In transcranial direct current stimulation (tDCS), the injected current becomes distributed across the brain areas. The objective is to stimulate the target region of interest (ROI) while minimizing the current in non-target ROIs (the 'focality' of tDCS). For this purpose, determining the appropriate current dose for an individual is difficult. Aim: To introduce a dose-target determination index (DTDI) to quantify the focality of tDCS and examine the dose-focality relationship in three different populations. Method: Here, we extended our previous toolbox i-SATA to the MNI reference space. After a tDCS montage is simulated for a current dose, the i-SATA(MNI) computes the average (over voxels) current density for every region in the brain. DTDI is the ratio o

SUBMITTER: Kashyap R 

PROVIDER: S-EPMC8466113 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature