Ontology highlight
ABSTRACT:
SUBMITTER: Li G
PROVIDER: S-EPMC8466207 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Li Guohui G Fu Wenxuan W Deng Yu Y Zhao Yunying Y
Genes 20210825 9
The calcium/calcineurin signalling pathway is required for cell survival under various environmental stresses. Using <i>Saccharomyces cerevisiae</i>, we explored the mechanism underlying calcium-regulated homeostasis of intracellular reactive oxygen species (ROS). We found that deletion of acyltransferase Akr1 and C-5 sterol desaturase Erg3 increased the intracellular ROS levels and cell death, and this could be inhibited by the addition of calcium. The hexose transporter Hxt1 and the amino acid ...[more]