Ontology highlight
ABSTRACT:
SUBMITTER: Calonge M
PROVIDER: S-EPMC8466237 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Calonge Margarita M Nieto-Miguel Teresa T de la Mata Ana A Galindo Sara S Herreras José M JM López-Paniagua Marina M
Pharmaceutics 20210916 9
Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure occurs due to malfunction or destruction of the limbal stem cell niche, upon which the superficial cornea depends for homeostatic maintenance and wound healing. Failure of the limbal niche is referred to as limbal stem cell deficiency. As the corneal epithelial stem cell niche is easily accessible, limbal stem cell-based therapy and regenerative medicine applied to the ocular surface are among the most ...[more]