A New Approach to Atopic Dermatitis Control with Low-Concentration Propolis-Loaded Cold Cream.

ABSTRACT: Atopic dermatitis (AD) is a chronic inflammatory skin disease that is difficult to treat. Traditional cold cream, a water-in-oil emulsion made from beeswax, is used to alleviate AD symptoms in clinical practice, although its effectiveness has not been scientifically proven. The addition of propolis has the potential to impart anti-inflammatory properties to cold cream. However, in high concentrations, propolis can trigger allergic reactions. Thus, the objective of this work was to develop a cold cream formulation based on purified beeswax containing the same amount of green propolis present in raw beeswax. The impact of adding this low propolis concentration to cold cream on AD control was evaluated in patients compared to cold cream without added propolis (CBlank). Raw beeswax was chemica

SUBMITTER: Martin BA 

PROVIDER: S-EPMC8466707 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature