Years of Schooling Could Reduce Epigenetic Aging: A Study of a Mexican Cohort.

ABSTRACT: Adverse conditions in early life, including environmental, biological and social influences, are risk factors for ill-health during aging and the onset of age-related disorders. In this context, the recent field of social epigenetics offers a valuable method for establishing the relationships among them However, current clinical studies on environmental changes and lifespan disorders are limited. In this sense, the Tlaltizapan (Mexico) cohort, who 52 years ago was exposed to infant malnutrition, low income and poor hygiene conditions, represents a vital source for exploring such factors. Therefore, in the present study, 52 years later, we aimed to explore differences in clinical/biochemical/anthropometric and epigenetic (DNA methylation) variables between individuals from such a cohort, in

SUBMITTER: Gomez-Verjan JC 

PROVIDER: S-EPMC8469534 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature