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DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility.

ABSTRACT: In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its high strength and elongation. It was revealed that an increase in the capacitor storage voltage results in the rise in sp2- and sp-hybridized carbon concentration, which makes it possible to control the chemical structure and surface energy of the modified surface. The experiments with 3T3L1 fibroblasts showed no toxic effects of the materials extracts.

SUBMITTER: Yuriev Y

PROVIDER: S-EPMC8470059 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility.

Yuriev Yuri Y Goreninskii Semen S Runts Artem A Prosetskaya Elisaveta E Plotnikov Evgenii E Shishkova Darya D Kudryavtseva Yulia Y Bolbasov Evgeny E

Membranes 20210907 9

In this paper, the results on the fabrication of ferroelectric membranes as vascular patches with modified surfaces are presented. For the modification of a membrane surface contacting blood, DLC coating was deposited using the pulsed vacuum arc deposition technique. The physico-chemical properties and cytotoxicity of the membranes modified under various conditions were studied. It was found that DLC coatings do not affect membrane microstructure, preserving its crystal structure as well as its ...[more]

PMID: 34564507

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Project description:The current evaluation was conducted to investigate the chemical composition and functional properties of protein hydrolysates from different Satureja species. The major amino acids (mg/100 g protein) in the protein from different Satureja species were arginine (6.06-14.37), asparagine (1.39-17.06), glutamine (2.42-11.60), glutamic acid (6.34-9.32), beta-aminoisobutyric acid (3.31-10.29), alanine (4.64-9.59), aspartic acid (5.73-9.54), proline (4.25-8.14), leucine (3.63-5.69), serine (2.64-4.83), lysine (1.89-4.56), glycine (0.96-5.27), valine (2.76-4.83), and phenylalanine (2.86-3.75). Protein hydrolysates from Satureja species exhibited comparable antioxidant activity (IC50 = 0.270-0.328 mg/mL), anti-linoleic acid oxidation (IC50 = 0.231-0.301 mg/mL), anti-lecithin oxidation (IC50 = 0.198-0.258 mg/mL), anti-starch oxidation (IC50 = 0.201-0.277 mg/mL), anti-amylase activity (IC50 = 0.314-0.337 mg/mL), and anti-lipase activity (IC50 = 0.309-0.369 mg/mL). The physico-chemical properties of gelatin dispersion were electrical conductivity (1197 microsiemens/cm), osmolarity (190 milliosmol/kg), surface tension (45 mN/m), particle size (179 nm), zeta potential (-48 mV), and viscosity (4.92 mPa.s). Techno-functional characteristics of freeze-dried gelatin particles were as follows: water content (7.68%), water solubility (84.57%), water swelling (151.33%), hygroscopicity (38.20%), hydrophobicity (6.50 μg/g), emulsification activity (68.54%), emulsification stability (57.86%), foam expansion activity (56.08%), foam stability (41.84%), oil-holding capacity (1.96 g/g), and water-holding capacity (4.45 g/g). Protein hydrolysate causes minor changes in the physico-chemical and techno-functional properties of gelatin. The current investigation introduces Satureja protein hydrolysate as a possible functional and techno-functional ingredient for bioactive food products for treating diabetes and oxidative stress and as a natural preservative for the food industry.

Dataset Information

DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility.

Publications

DLC-Coated Ferroelectric Membranes as Vascular Patches: Physico-Chemical Properties and Biocompatibility.

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