Genetic Diversity of Microneme Protein 2 and Surface Antigen 1 of Eimeria tenella.

ABSTRACT: Avian coccidiosis is a disease caused by members of the genus Eimeria. Huge economic losses incurred by the global poultry industry due to coccidiosis have increased the need for cost-effective and easily available recombinant vaccines. Microneme protein 2 (MIC2) and surface antigen 1 (SAG1) of E. tenella have been recognised as potential vaccine candidates. However, the genetic diversity of the antigens in field isolates, which affects vaccine efficacy, has yet to be largely investigated. Here, we analysed genetic diversity and natural selection of etmic2 and etsag1 in Korean E. tenella isolates. Both genes exhibited low levels of genetic diversity in Korean isolates. However, the two genes showed different patterns of nucleotide diversity and amino acid

SUBMITTER: Vo TC 

PROVIDER: S-EPMC8470435 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature