Ontology highlight
ABSTRACT:
SUBMITTER: Kotani O
PROVIDER: S-EPMC8473006 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Kotani Osamu O Suzuki Yasushi Y Saito Shinji S Ainai Akira A Ueno Akira A Hemmi Takuya T Sano Kaori K Tabata Koshiro K Yokoyama Masaru M Suzuki Tadaki T Hasegawa Hideki H Sato Hironori H
Viruses 20210831 9
The stalk domain of influenza virus envelope glycoprotein hemagglutinin (HA) constitutes the axis connecting the head and transmembrane domains, and plays pivotal roles in conformational rearrangements of HA for virus infection. Here we characterized molecular interactions between the anti-HA stalk neutralization antibody F11 and influenza A(H1N1)pdm09 HA to understand the structural basis of the actions and modifications of this antibody. In silico structural analyses using a model of the trime ...[more]