Ontology highlight
ABSTRACT:
SUBMITTER: Beddingfield BJ
PROVIDER: S-EPMC8473068 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Beddingfield Brandon J BJ Hartnett Jessica N JN Wilson Russell B RB Kulakosky Peter C PC Andersen Kristian G KG Robles-Sikisaka Refugio R Grubaugh Nathan D ND Aybar Argelia A Nunez Maria-Zunilla MZ Fermin Cesar D CD Garry Robert F RF
Viruses 20210905 9
Infection with Zika virus (ZIKV), a member of the <i>Flavivirus</i> genus of the <i>Flaviviridae</i> family, typically results in mild self-limited illness, but severe neurological disease occurs in a limited subset of patients. In contrast, serious outcomes commonly occur in pregnancy that affect the developing fetus, including microcephaly and other major birth defects. The genetic similarity of ZIKV to other widespread flaviviruses, such as dengue virus (DENV), presents a challenge to the dev ...[more]