The Input of Structural Vaccinology in the Search for Vaccines against Bunyaviruses.

ABSTRACT: A significant increase in the number of viruses causing unexpected illnesses and epidemics among humans, wildlife and livestock has been observed in recent years. These new or re-emerging viruses have often caught the scientific community off-guard, without sufficient knowledge to combat them, as shown by the current coronavirus pandemic. The bunyaviruses, together with the flaviviruses and filoviruses, are the major etiological agents of viral hemorrhagic fever, and several of them have been listed as priority pathogens by the World Health Organization for which insufficient countermeasures exist. Based on new techniques allowing rapid analysis of the repertoire of protective antibodies induced during infection, combined with atomic-level structural information on viral surface proteins,

SUBMITTER: Serris A 

PROVIDER: S-EPMC8473429 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature