Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium-zinc-telluride-based SPECT/CT system: a phantom study.

ABSTRACT:

Background

The digital cadmium-zinc-telluride (CZT)-based SPECT system has many advantages, including better spatial and energy resolution. However, the impacts of different acquisition and reconstruction parameters on CZT SPECT quantification might still need to be validated. This study aimed to evaluate the impacts of acquisition parameters (the main energy window and acquisition time per frame) and reconstruction parameters (the number of iterations, subsets in iterative reconstruction, post-filter, and image correction methods) on the technetium quantification of CZT SPECT/CT.

Methods

A phantom (PET NEMA/IEC image quality, USA) was filled with four target-to-background (T/B) ratios (32:1, 16:1, 8:1, and 4:1) of technetium. Mean uptake values (the calculated mean concentr

SUBMITTER: Zhang R 

PROVIDER: S-EPMC8473509 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature