Individuals with substance use disorders have a distinct oral microbiome pattern.

ABSTRACT:

Background

Substance use disorder emerges from a complex interaction between genetic predisposition, life experiences, exposure, and subsequent adaptation of biological systems to the repeated use of drugs. Recently, investigators have proposed that the human microbiota may play a role in brain health and disease. In particular, the human oral microbiome is a distinct and diverse ecological niche with its composition influenced by external factors such as lifestyle, diet, and oral hygiene. This investigation examined whether individuals with substance use disorder (SU) show a different oral microbiome pattern and whether this pattern is sufficient to delineate the SU group from healthy comparison (HC) subjects.

Methods

Participants were a sub-sample (N ​= ​177) of the Tulsa

SUBMITTER: Kosciolek T 

PROVIDER: S-EPMC8474247 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature