The yield of tuberculosis contact investigation in low- and middle-income settings: a systematic review and meta-analysis.

ABSTRACT:

Background

Contact investigation, the systematic evaluation of individuals in close contact with an infectious tuberculosis (TB) patient, is a key active case-finding strategy for global TB control. Better estimates of the yield of contact investigation can guide strategies to reduce the number of underreported and underdiagnosed TB cases, approximately three million cases per year globally. A systematic review (Prospero ID # CRD42019133380) and meta-analysis was conducted to update and enhance the estimates of the yield of TB contact investigation in low- and middle-income countries (LMIC). Pubmed, Web of Science, Embase and the WHO Global Index Medicus were searched for peer-reviewed studies (published between January 2006-April 2019); studies reporting the number of active TB or

SUBMITTER: Velleca M 

PROVIDER: S-EPMC8474777 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature