Association of retroperitoneal fibrosis with malignancy and its outcomes.

ABSTRACT:

Introduction

Retroperitoneal fibrosis (RPF) is characterized by a highly fibrotic retroperitoneal mass and encompasses the idiopathic form and secondary to malignancies. Because we have limited knowledge whether RPF is associated with malignancy, we aimed to investigate the relationship between RPF and malignancy and to compare the characteristics and prognosis of cancers among patients with RPF.

Methods

Medical records of 111 patients diagnosed as having RPF were reviewed and 38 cases of cancer, confirmed by biopsy, were identified. Standardized incidence ratios (SIRs) were calculated for cancers and stratified according to cancer type and RPF-cancer diagnosis interval. Cancer characteristics and outcomes were compared between RPF-cancer diagnosis intervals.

Results

SUBMITTER: Lee SJ 

PROVIDER: S-EPMC8474894 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature