Early kidney injury predicts disease progression in patients with COVID-19: a cohort study.

ABSTRACT:

Background

The receptor of severe respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2, is more abundant in kidney than in lung tissue, suggesting that kidney might be another important target organ for SARS-CoV-2. However, our understanding of kidney injury caused by Coronavirus Disease 2019 (COVID-19) is limited. This study aimed to explore the association between kidney injury and disease progression in patients with COVID-19.

Methods

A retrospective cohort study was designed by including 2630 patients with confirmed COVID-19 from Huoshenshan Hospital (Wuhan, China) from 1 February to 13 April 2020. Kidney function indexes and other clinical information were extracted from the electronic medical record system. Associations between kidney functi

SUBMITTER: Xia T 

PROVIDER: S-EPMC8474921 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature