Role of neutrophil-to-lymphocyte ratio as a prognostic biomarker in patients with breast cancer receiving neoadjuvant chemotherapy: a meta-analysis.

ABSTRACT:

Objective

The neutrophil-to-lymphocyte ratio (NLR) is recognised as a suitable prognostic biomarker in patients with breast cancer. Nevertheless, the efficacy of this biomarker in predicting the pathological complete response (pCR) and survival in patients with breast cancer receiving neoadjuvant chemotherapy (NACT) is still controversial. This meta-analysis aimed to identify the association between baseline NLR and the prognosis of patients with breast cancer treated with NACT.

Design

Meta-analysis.

Data sources

Relevant literature published before 1 May 2021 was searched using the Cochrane Library, Embase, PubMed and the Web of Science databases.

Eligibility criteria

All studies involving patients with breast cancer treated with NACT and peripheral blood pret

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC8475153 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature