Long-term neuropsychological outcomes of survivors of young childhood brain tumors treated on the Head Start II protocol.

ABSTRACT:

Background

The Head Start treatment protocols have focused on curing young children with brain tumors while avoiding or delaying radiotherapy through using a combination of high-dose, marrow-ablative chemotherapy and autologous hematopoietic cell transplantation (AuHCT). Late effects data from treatment on the Head Start II (HS II) protocol have previously been published for short-term follow-up (STF) at a mean of 39.7 months post-diagnosis. The current study examines long-term follow-up (LTF) outcomes from the same cohort.

Methods

Eighteen HS II patients diagnosed with malignant brain tumors <10 years of age at diagnosis completed a neurocognitive battery and parents completed psychological questionnaires at a mean of 104.7 months' post-diagnosis.

Results

There was n

SUBMITTER: Levitch CF 

PROVIDER: S-EPMC8475224 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature