The Impact of Rheumatoid Arthritis on Bone Loss: Links to Osteoporosis and Osteopenia.

ABSTRACT: Rheumatoid arthritis (RA) is an autoimmune chronic connective tissue disease that produces persistent systemic inflammation, with joint inflammation leading to function loss and joint destruction. Low bone mass causes skeletal bone loss, commonly referred to as osteopenia or osteoporosis.  We conducted this literature review to examine the relationship between RA and osteoporosis and the variables contributing to this connection. We used articles from the US National Library of Medicine (PubMed), Google Scholar, Science Direct to access the required information. Eventually, our results concluded that RA could result in local periarticular and generalized bone loss. Many risk factors contribute to this association, such as chronic joints inflammation, glucocorticoid use, genetics, and estro

SUBMITTER: Kareem R 

PROVIDER: S-EPMC8476196 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature