Prognostic significance of viable tumor size measurement in hepatocellular carcinomas after preoperative locoregional treatment.

ABSTRACT:

Background

Preoperative locoregional treatment (LRT) for hepatocellular carcinoma (HCC) often induces intratumoral necrosis without affecting the overall tumor size, and residual viable tumor size (VTS) on imaging is an important clinical parameter for assessing post-treatment response. However, for surgical specimens, it is unclear whether the VTS would be more relevant to prognosis compared to total tumor size (TTS).

Methods

A total of 142 surgically resected solitary HCC cases were retrospectively reviewed. The TTS and VTS were assessed by applying the modified Response Evaluation Criteria in Solid Tumors method to the resected specimens, and correlated with the clinicopathological features and survival.

Results

As applying VTS, 13/142 cases (9.2%) were down-staged

SUBMITTER: Hwang YJ 

PROVIDER: S-EPMC8476315 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature