Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery.

ABSTRACT: Background: Cardio-regenerative cell therapies offer additional biologic support to coronary artery bypass surgery (CABG) and are aimed at functionally repairing the myocardium that suffers from or is damaged by ischemia. This non-randomized open-label study assessed the safety and feasibility of epicardial transplantation of atrial appendage micrografts (AAMs) in patients undergoing CABG surgery. Methods: Twelve consecutive patients destined for CABG surgery were included in the study. Six patients received AAMs during their operation and six patients were CABG-operated without AAMs transplantation. Data from 30 elective CABG patients was collected for a center- and time-matched control group. The AAMs were processed during the operation from a biopsy collected from the righ

SUBMITTER: Nummi A 

PROVIDER: S-EPMC8476794 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature