Effectiveness of corticosteroids on chest high-resolution computed tomography features of COVID-19 pneumonia.

ABSTRACT:

Objective

The aim of our study was to assess the effect of a short-term treatment with low-moderate corticosteroid (CS) doses by both a quantitative and qualitative assessment of chest HRCT of COVID-19 pneumonia.

Methods

CORTICOVID is a single-center, cross-sectional, retrospective study involving severe/critical COVID-19 patients with mild/moderate ARDS. Lung total severity score was obtained according to Chung and colleagues. Moreover, the relative percentages of lung total severity score by ground glass opacities, consolidations, crazy paving, and linear bands were computed. Chest HRCT scores, P/F ratio, and laboratory parameters were evaluated before (pre-CS) and 7-10 days after (post-CS) methylprednisolone of 0.5-0.8 mg/kg/day.

Findings

A total of 34 severe/criti

SUBMITTER: Calabrese C 

PROVIDER: S-EPMC8477677 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature