Fully amorphous atactic and isotactic block copolymers and their self-assembly into nano- and microscopic vesicles.

ABSTRACT: The introduction of chirality into aqueous self-assemblies by employing isotactic block copolymers (BCPs) is an emerging field of interest as it promises special membrane properties of polymersomes not accessible by atactic BCPs. However, isotactic BCPs typically exhibit crystalline behaviour, inducing high membrane stiffness and limiting their applicability in systems involving membrane proteins or sensitive cargo. In this study, an isotactic yet fully amorphous BCP is introduced which overcomes these limitations. Three BCPs composed of poly(butylene oxide)-block-poly(glycidol) (PBO-b-PG), differing solely in their tacticities (R/S, R and S), were synthesised and characterised regarding their structural, optical and thermal properties. Their self-

SUBMITTER: Wehr R 

PROVIDER: S-EPMC8477912 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature