Gastric microbiome in horses with and without equine glandular gastric disease.

ABSTRACT:

Background

The role of the gastric microbiome in development or persistence of equine glandular gastric disease (EGGD) remains to be investigated.

Hypothesis/objectives

The objective was to characterize the glandular mucosal and gastric fluid microbiomes of horses with and without EGGD. It was hypothesized that differences in the mucosal microbiome are associated with EGGD.

Animals

Twenty-four horses were enrolled.

Methods

Gastroscopy was performed and EGGD scores recorded (score 0, n = 6; score 1, n = 8; score ≥2, n = 10). Gastric fluid and pinch biopsies of healthy glandular mucosa and EGGD lesions were collected via gastroscope. 16S rRNA amplicon sequencing of the gastric fluid and glandular mucosal biopsies was performed. Relationships between gastric fluid

SUBMITTER: Paul LJ 

PROVIDER: S-EPMC8478018 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature