A New Approach for Classifying Fetal Growth Restriction.

ABSTRACT:

Background

Fetal growth restriction is commonly defined using small for gestational age (SGA) birth (birthweight < 10th percentile) as a proxy, but this approach is problematic because most SGA infants are small but healthy. In this proof-of-concept study, we sought to develop a new approach for identifying fetal growth restriction at birth that combines information on multiple, imperfect measures of fetal growth restriction in a probabilistic manner.

Methods

We combined information on birthweight, placental weight, placental malperfusion lesions, maternal disease, and fetal acidemia using latent profile analysis to classify fetal growth in births at the Royal Victoria Hospital in Montreal, Canada, 2001-2009. We examined the clinical characteristics and health outcomes of in

SUBMITTER: Hutcheon JA 

PROVIDER: S-EPMC8478298 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature