Radiological and functional evidence of the bronchial spread of tuberculosis: an observational analysis.

ABSTRACT:

Background

Direct bronchial spread of tuberculosis was extensively described in pre-antibiotic human pathology literature but this description has been overlooked in the post-antibiotic era, in which most pathology data come from animal models that emphasise the granuloma. Modern techniques, such as [¹⁸F]2-fluoro-2-deoxy-D-glucose (FDG) PET-CT scans, might provide further insight. Our aim was to understand normal early tuberculosis resolution patterns on pulmonary PET-CT scans in treated patients with tuberculosis who were subsequently cured.

Methods

In this observational analysis, we analysed data from PredictTB, an ongoing, prospective, randomised clinical trial that examined sequential baseline and week 4 FDG-PET-CT scans from participants successfully treated

SUBMITTER: Chen RY 

PROVIDER: S-EPMC8478663 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature