Pharmacological Treatments for Borderline Personality Disorder: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Borderline personality disorder (BPD) is a debilitating psychiatric disorder that affects 0.4-3.9% of the population in Western countries. Currently, no medications have been approved by regulatory agencies for the treatment of BPD. Nevertheless, up to 96% of patients with BPD receive at least one psychotropic medication.

Objectives

The objective of this systematic review was to assess the general efficacy and the comparative effectiveness of different pharmacological treatments for BPD patients.

Methods

We conducted systematic literature searches limited to English language in MEDLINE, EMBASE, the Cochrane Library, and PsycINFO up to April 6, 2021, and searched reference lists of pertinent articles and reviews. Inclusion criteria were (i) patients 13 years

SUBMITTER: Gartlehner G 

PROVIDER: S-EPMC8478737 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature