18 F-FDG-PET/MRI in patients with Graves' orbitopathy.

ABSTRACT:

Purpose

Currently, therapeutic management of patients with Graves' orbitopathy (GO) relies on clinical assessments and MRI. However, monitoring of inflammation remains difficult since external inflammatory signs do not necessarily represent the orbital disease activity. Therefore, we aimed to evaluate the diagnostic value of ¹⁸F-FDG-PET/MRI to assess the inflammation of GO patients.

Methods

Enrolled patients with new onset of GO underwent ophthalmological examinations to evaluate the activity (CAS) and severity of GO (NOSPECS), as well as an ¹⁸F-FDG-PET/MRI (Siemens Biograph mMR) with dual time point imaging (immediately post-injection and 60 min p.i.). A subset of PET parameters including maximum standardized uptake value (SUVmax), metabolic target vol

SUBMITTER: Weber M 

PROVIDER: S-EPMC8478760 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature