Parkinson's disease aggravation in association with fine particle components in New York State.

ABSTRACT:

Background

Long-term exposure to fine particulate matter (PM_2.5) has been associated with neurodegenerative diseases, including disease aggravation in Parkinson's disease (PD), but associations with specific PM_2.5 components have not been evaluated.

Objective

To characterize the association between specific PM_2.5 components and PD first hospitalization, a surrogate for disease aggravation.

Methods

We obtained data on hospitalizations from the New York Department of Health Statewide Planning and Research Cooperative System (2000-2014) to calculate annual first PD hospitalization counts in New York State per county. We used well-validated prediction models at 1 km² resolution to estimate county level population-weighted annual

SUBMITTER: Nunez Y 

PROVIDER: S-EPMC8478789 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature