A randomized trial of exercise and diet on health-related quality of life in survivors of breast cancer with overweight or obesity.

ABSTRACT:

Background

Obesity is a chronic, relapsing, and progressive disease; it is associated with poor health-related quality of life (HRQOL) in survivors of breast cancer.

Methods

In this 2 × 2 factorial trial, 351 survivors of breast cancer with overweight or obesity were randomized to 1 of 4 treatment groups for 52 weeks: control, exercise alone, diet alone, or exercise plus diet. HRQOL end points were measured at baseline and at week 52 using the 36-Item Medical Outcomes Survey-Short Form (SF-36). Repeated measures analysis of covariance quantified the estimated treatment difference (ETD).

Results

At baseline, participants had a mean (SD) age of 59.4 years (8.7), body mass index of 34.0 kg/m² (5.9), and 71 participants (20.2%) self-reported fair or poor genera

SUBMITTER: Brown JC 

PROVIDER: S-EPMC8478822 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature