Quantitative EEG improves prediction of Sturge-Weber syndrome in infants with port-wine birthmark.

ABSTRACT:

Objective

Port-wine birthmark (PWB) is a common occurrence in the newborn, and general pediatricians, dermatologists, and ophthalmologists are often called on to make an assessment of risk for Sturge-Weber syndrome (SWS) due to workforce shortages in pediatric neurologists and MRI's low sensitivity for SWS brain involvement in infants. We therefore aimed to develop a quantitative EEG (qEEG) approach to safely screen young infants with PWB for SWS risk and optimal timing of diagnostic MRI.

Methods

Forty-eight infants (prior to first birthday) underwent EEG recording. Signal processing methods compared voltage between left and right sides using a previously defined pipeline and diagnostic threshold. In this test sample, we compared sensitivity/specificity of the qEEG metric ag

SUBMITTER: Gill RE 

PROVIDER: S-EPMC8478826 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature