Spatial modulation of dark versus bright stimulus responses in the mouse visual system.

ABSTRACT: A fundamental task of the visual system is to respond to both increases and decreases of luminance with action potentials (ON and OFF responses^1-4). OFF responses are stronger, faster, and more salient than ON responses in primary visual cortex (V1) of both cats^5,6 and primates,^7,8 but in ferrets⁹ and mice,¹⁰ ON responses can be stronger, weaker,¹¹ or balanced¹² in comparison to OFF responses. These discrepancies could arise from differences in species, experimental techniques, or stimulus properties, particularly retinotopic location in the visual field, as has been speculated;⁹ however, the role of retinotopy for ON/OFF dominance has not been systematically

SUBMITTER: Williams B 

PROVIDER: S-EPMC8478832 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature