Oxytocin, PTSD, and sexual abuse are associated with attention network intrinsic functional connectivity.

ABSTRACT: Childhood maltreatment is linked to Posttraumatic Stress Disorder (PTSD) in adulthood. Neural attention network function contributes to resilience against PTSD following maltreatment; oxytocin administration alters functional connectivity differentially among resilient to PTSD groups. The present study examined intrinsic connectivity between ventral and dorsal neural attention networks (VAN and DAN) to clarify the nature of dysfunction versus resilience in the context of maltreatment-related PTSD, and to explore differential dysfunction related to varied aspects of maltreatment. Oxytocin administration was examined as a factor in these relationships. Resting-state functional connectivity data were collected from 39 adults with maltreatment histories, with and without PTSD, who were randoml

SUBMITTER: Crum KI 

PROVIDER: S-EPMC8478844 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature