Ontology highlight
ABSTRACT:
SUBMITTER: Gautam P
PROVIDER: S-EPMC8478974 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Gautam Pradeep P Hamashima Kiyofumi K Chen Ying Y Zeng Yingying Y Makovoz Bar B Parikh Bhav Harshad BH Lee Hsin Yee HY Lau Katherine Anne KA Su Xinyi X Wong Raymond C B RCB Chan Woon-Khiong WK Li Hu H Blenkinsop Timothy A TA Loh Yuin-Han YH
Nature communications 20210928 1
The retina is a widely profiled tissue in multiple species by single-cell RNA sequencing studies. However, integrative research of the retina across species is lacking. Here, we construct the first single-cell atlas of the human and porcine ocular compartments and study inter-species differences in the retina. In addition to that, we identify putative adult stem cells present in the iris tissue. We also create a disease map of genes involved in eye disorders across compartments of the eye. Furth ...[more]