The Association Between Mean Glycated Haemoglobin or Glycaemic Variability and the Development of Retinopathy in People with Diabetes: A Retrospective Observational Cohort Study.

ABSTRACT:

Introduction

To determine the association between mean glycated haemoglobin (HbA_1c) or glycaemic variability and the development of diabetic retinopathy (DR) in people with diabetes.

Methods

An observational cohort study with people registered with a DR eye screening service between October 2012 and October 2017. Those who had no DR at the start of the study were followed for a maximum of 5 years. HbA_1c measures were used to calculate HbA_1c variability and mean HbA_1c to assess any relationship between these and the risk of developing new onset DR.

Results

A total of 2511 individuals were followed up for up to 5 years. Of these, 542 (21.6%) developed DR. After adjustment, HbA_1c variability was not significantly ass

SUBMITTER: Dhatariya K 

PROVIDER: S-EPMC8479058 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature